REGRESSION: Yes, does not occur in 4.15
Crash occurs when the user adds a Preview Scene Profile while in the animation or skeletal mesh editor, and then removes it while in the animation blueprint editor (or vice versa).
This occurs on both Mac and Windows.
RESULT
Crash
UE4Editor-AdvancedPreviewScene.dylib!FAdvancedPreviewScene::OnAssetViewerSettingsRefresh() UE4Editor-AdvancedPreviewScene.dylib!TBaseRawMethodDelegateInstance<false, FAdvancedPreviewScene, void ()>::ExecuteIfSafe() UE4Editor-AdvancedPreviewScene.dylib!TBaseMulticastDelegate<void, FName const&>::Broadcast() UE4Editor-AdvancedPreviewScene.dylib!FAdvancedPreviewScene::SetProfileIndex() UE4Editor-AdvancedPreviewScene.dylib!SAdvancedPreviewDetailsTab::ComboBoxSelectionChanged(TSharedPtr<FString,() UE4Editor-AdvancedPreviewScene.dylib!<Unknown> UE4Editor-AdvancedPreviewScene.dylib!TBaseSPMethodDelegateInstance<false, SAdvancedPreviewDetailsTab, (ESPMode)0, TTypeWrapper<void> (TSharedPtr<FString, (ESPMode)0> UE4Editor-AdvancedPreviewScene.dylib!TBaseSPMethodDelegateInstance<false, SAdvancedPreviewDetailsTab, (ESPMode)0, void (TSharedPtr<FString, (ESPMode)0>, ESelectInfo: UE4Editor-Slate.dylib!TBaseDelegate<void, TSharedPtr<FString, (ESPMode)0>, ESelectInfo::Type>::ExecuteIfBound(TSharedPtr<FString,() UE4Editor-Slate.dylib!STextComboBox::OnSelectionChanged(TSharedPtr<FString,() UE4Editor-Slate.dylib!<Unknown> UE4Editor-Slate.dylib!TBaseSPMethodDelegateInstance<false, STextComboBox, (ESPMode)0, TTypeWrapper<void> (TSharedPtr<FString, (ESPMode)0>, ESelectInfo UE4Editor-Slate.dylib!TBaseSPMethodDelegateInstance<false, STextComboBox, (ESPMode)0, void (TSharedPtr<FString, (ESPMode)0>, ESelectInfo::Type)>::Exec UE4Editor-Slate.dylib!TBaseDelegate<void, TSharedPtr<FString, (ESPMode)0>, ESelectInfo::Type>::ExecuteIfBound(TSharedPtr<FString,() UE4Editor-Slate.dylib!SComboBox<TSharedPtr<FString, (ESPMode)0> >::OnSelectionChanged_Internal(TSharedPtr<FString,() UE4Editor-Slate.dylib!<Unknown> UE4Editor-Slate.dylib!TBaseSPMethodDelegateInstance<false, SComboBox<TSharedPtr<FString, (ESPMode)0> >, (ESPMode)0, TTypeWrapper<void> (TSharedPtr<FSt UE4Editor-Slate.dylib!TBaseSPMethodDelegateInstance<false, SComboBox<TSharedPtr<FString, (ESPMode)0> >, (ESPMode)0, void (TSharedPtr<FString, (ESPMode UE4Editor-Slate.dylib!TBaseDelegate<void, TSharedPtr<FString, (ESPMode)0>, ESelectInfo::Type>::ExecuteIfBound(TSharedPtr<FString,() UE4Editor-Slate.dylib!SListView<TSharedPtr<FString, (ESPMode)0> >::Private_SignalSelectionChanged() UE4Editor-Slate.dylib!SListView<TSharedPtr<FString, (ESPMode)0> >::SetItemSelection(TSharedPtr<FString,() UE4Editor-Slate.dylib!SComboBox<TSharedPtr<FString, (ESPMode)0> >::SetSelectedItem(TSharedPtr<FString,() UE4Editor-Slate.dylib!STextComboBox::SetSelectedItem(TSharedPtr<FString,() UE4Editor-AdvancedPreviewScene.dylib!SAdvancedPreviewDetailsTab::UpdateProfileNames() UE4Editor-AdvancedPreviewScene.dylib!SAdvancedPreviewDetailsTab::Refresh() UE4Editor-AdvancedPreviewScene.dylib!TBaseFunctorDelegateInstance<void (), SAdvancedPreviewDetailsTab::SAdvancedPreviewDetailsTab()::$_2>::ExecuteIfSafe() UE4Editor-AdvancedPreviewScene.dylib!TBaseMulticastDelegate<void>::Broadcast() UE4Editor-AdvancedPreviewScene.dylib!UAssetViewerSettings::PostEditChangeProperty() UE4Editor-CoreUObject.dylib!UObject::PostEditChange() UE4Editor-AdvancedPreviewScene.dylib!SAdvancedPreviewDetailsTab::RemoveProfileButtonClick() UE4Editor-AdvancedPreviewScene.dylib!TBaseSPMethodDelegateInstance<false, SAdvancedPreviewDetailsTab, (ESPMode)0, FReply ()>::Execute() UE4Editor-Slate.dylib!SButton::OnMouseButtonUp() UE4Editor-Slate.dylib!FSlateApplication::RoutePointerUpEvent() UE4Editor-Slate.dylib!FSlateApplication::ProcessMouseButtonUpEvent() UE4Editor-Slate.dylib!FSlateApplication::OnMouseUp() UE4Editor-Core.dylib!FMacApplication::ProcessEvent() UE4Editor-Core.dylib!FMacApplication::ProcessDeferredEvents() UE4Editor-Slate.dylib!FSlateApplication::TickPlatform() UE4Editor-Slate.dylib!FSlateApplication::Tick() UE4Editor!FEngineLoop::Tick() UE4Editor!GuardedMain() UE4Editor!<Unknown> UE4Editor-Core.dylib!<Unknown> Foundation!Unknown() libsystem_pthread.dylib!<Unknown> libsystem_pthread.dylib!<Unknown> libsystem_pthread.dylib!<Unknown>
There's no existing public thread on this issue, so head over to Questions & Answers just mention UE-43998 in the post.