Disabling any plugin causes packaging failure.
No repro in 4.19
Also occurring when Disabling all platforms except for windows and changing configuration from development to shipping.
Result: 4.20 - no .exe in WindowsNoEditor folder
4.21 - Error message:
"Missing UE4Game binary. You may have to build the UE4 project with your IDE. Alternatively, build using UnrealBuildTool with the commandline: UE4Game <Platform> <Configuration>"
Workaround: Enable any plugin (a different plugin then the one you originally disabled) - this will fix the project so that if this plugin is disabled packaging/exe creaton will succeed.
There's no existing public thread on this issue, so head over to Questions & Answers just mention UE-65006 in the post.