With the Draw debug points node, the points do not draw at the same sizes in Orthographic viewports as they do in Perspective viewports. This issue does not appear to be a regression.
Versions Tested: Issue occurs in all versions tested
4.15.3 - CL: 3450819
4.16.3 - CL: 3561208
4.17.2 - CL: 3658906
4.18.0 - CL: 3709383
There's no existing public thread on this issue, so head over to Questions & Answers just mention UE-51759 in the post.