HUD drawing does not update correctly when the user changes the viewport resolution, resulting in unexpected offset.
Safe zones appear to get stuck being enabled even after changing resolution preset to something without a safe zone.
The drawn line no longers goes to the corners of the viewport. If you restart the editor and PIE again, it's correct again.
There's no existing public thread on this issue, so head over to Questions & Answers just mention UE-92771 in the post.