I think this could occur anytime but is probably very rare. However using this plugin from the reported UDN makes it much easier to repro as they are calling FMacApplication::ConvertCocoaPositionToSlate() on a non-game thread.
See more info at:
[Link Removed]
There's no existing public thread on this issue, so head over to Questions & Answers just mention UE-121896 in the post.